What are the Different Types of Depression?

Sam Clinch • May 29, 2024

Major Depressive Disorder (MDD) is a common mental health condition characterized by relentless feelings of sadness, loss of interest in activities, and low energy. However, this condition can present in various ways from person to person. There are 6 subtypes of clinical depression: melancholic, anxious, atypical, psychotic, seasonal, and postpartum depression.  While there are distinct types of depression, each share common core symptoms. A detailed psychiatric evaluation is needed in order to diagnose any potential depressive subtypes. This additional exploration may help individuals better understand their depression and achieve better treatment outcomes. Read on to learn more about the features, challenges, and risk factors of the 6 subtypes of depression.

Melancholic Depression

25-30% of the depressed population is affected by melancholic depression, a type of depression categorized by severe feelings of emptiness, despair, and guilt that are unreactive to circumstances. Distinguishing features include a worsening of symptoms in the morning, inability to feel pleasure, weight loss, and insomnia from waking too early. 


Learn more about
TMS treatment for depression →


Furthermore, individuals with melancholic depression rarely respond to psychotherapy or social interventions, suggesting a strong biological component. Hypercortisol has also been found to be associated with melancholia. Individuals with this depressive subtype are at a higher risk for unemployment.

Anxious Depression

Anxious depression is distinct from other subtypes because it includes symptoms of anxious distress. In addition to low mood and/or loss of interest in daily activities, individuals with anxious depression experience at least two of the following symptoms: restlessness, difficulty concentrating due to excessive worry, fear that something terrible might happen, feeling tense, or feeling that they might lose control of themselves. Although this depressive subtype can appear similar to comorbid anxiety and depression, it is distinct because individuals with anxious depression don’t actually meet the diagnostic criteria for an anxiety disorder.

 
Learn more about
TMS for anxiety →


It is estimated that
54-78% of individuals with depression also experience anxious distress. This distress is significant, and individuals with anxious depression experience more functional impairment with relationships, work, home life, and social situations. Women and individuals with a history of trauma or abuse are more likely to have anxious depression than non-anxious depression.

Atypical Depression

20-30% of depressed patients exhibit atypical depression, a type of depression characterized by the ability to temporarily feel better in response to positive external events (mood reactivity), severe fatigue, hypersomnia, and increased appetite. Additionally, atypical depression appears to have an earlier age of onset and a chronic, long-lasting presentation. A key feature of atypical depression is rejection sensitivity where the patient frequently has an excessive response to rejection, leading to social impairment. Although it is not part of the diagnostic criteria, symptoms of atypical depression tend to worsen at night. Atypical depression may present more often in bipolar disorder, especially bipolar disorder type II. Two-thirds of the cases of atypical depression can also report symptoms of bipolarity. 

Psychotic Depression

Psychotic depression is a subtype of major depression that includes primary symptoms of psychosis, hallucinations and/or delusions. Hallucinations are false sensory perceptions such as seeing or hearing things that aren’t real. Delusions are false, fixed beliefs. The delusions and hallucinations are almost always related to the individual’s depressed mood. For example, a patient might hear voices criticizing them, or telling them that they’re to blame for something.   It is estimated that 10-15% of the depressed population also exhibit psychosis. Depressed individuals over the age of 60 are more likely to have psychotic depression. Furthermore, patients with psychotic depression are at a much higher risk for suicide than non-psychotic depression. Individuals with active psychosis are out of touch with reality and often feel as if they are not in control of their life. Psychosis results in difficulties deciphering what is real and what is imagined, making everyday activities extremely challenging.

Seasonal Depression

 An estimated 0.5-2.4% of the general population and 10-20% of those diagnosed with major depression are affected by seasonal depression (also known as seasonal affective disorder or SAD), a subtype of depression that features season-specific depression. 90% of those with seasonal depression experience a winter-pattern with symptoms present in the winter months and absent in the spring and summer. Specific symptoms include hypersomnia, increased appetite, and social withdrawal. The remaining 10% exhibit a summer-pattern where symptoms including insomnia and decreased appetite appear in the summer months and subside in the fall and winter. Although the causes of seasonal affective disorder are complex, circadian rhythm disruption due to shifted night-day cycle contributes to the development of the disorder.

Postpartum Depression

Postpartum depression is a type of major depression that specifically appears during pregnancy or within the first four weeks following delivery. Relentless feelings of sadness, emptiness, and low mood affect the individual’s ability to function and adjust to their new baby. Although the research is less prevalent, postpartum depression can also affect fathers. First-time mothers and fathers have a higher risk of postpartum depression. The drastic change in hormones during and after pregnancy are implicated in postpartum depression. Although it is less common, postpartum depression can sometimes include psychotic features.


Read more onTMS for Postpartum Depression →

While all types of major depression share many primary features, understanding what makes your depression unique can help you better understand your specific needs and potentially improve treatment outcomes with treatment more targeted to your depression subtype. A detailed assessment is necessary in order to properly identify any depressive specifiers. TMS Therapy can be an effective treatment for all subtypes of depression. Contact us to learn if TMS is right for you!

Every Question Answered

Want to know more about TMS? Check out this in-depth guide to TMS therapy with transparent and easy to understand explanations about TMS processes, protocols, and treated conditions.

Latest Posts

Woman in blue scrubs standing in front of an Inspire TMS Denver sign.
By Sam Clinch September 17, 2026
Stopped antidepressants because of the side effects? TMS avoids the systemic effects, weight gain, low libido, numbness, that make medication hard to tolerate.
Clinician adjusting a head-mounted device on a seated patient in a bright medical office
By Sam Clinch September 17, 2026
Tried two or more antidepressants without relief? TMS is FDA-cleared for exactly that. An honest look at how it works when medication hasn't, and who it's for.
Five healthcare staff in blue scrubs standing together in a clinic hallway, smiling at the camera
By Sam Clinch September 15, 2026
Does TMS cause weight gain? No. It's weight-neutral, unlike many antidepressants. Here's the honest reason why, and what any weight change during treatment means.
Clinician in blue scrubs adjusts a scalp treatment device on a smiling patient in a clinic chair
By Sam Clinch September 15, 2026
Does TMS affect memory? No, it's not linked to lasting memory loss, and it isn't ECT. Here's the honest picture, including why your focus may actually improve.
Four healthcare staff in blue scrubs standing together in a clinic hallway, smiling at the camera.
By Sam Clinch September 15, 2026
Is TMS safe? A straight look at the real side effects, the rare serious risks, and the truth behind "TMS ruined my life" stories, so you can decide clearly.
By Sam Clinch August 25, 2026
Quick Answer: Yes. TriCare covers TMS for adults with major depressive disorder on an outpatient basis. TriCare is accepted at Inspire TMS Denver, and your benefits are checked before treatment begins so you know your costs up front. TMS is FDA-cleared for depression, and if antidepressants have not worked, it may be a covered next step. Depression is common in the military community, and it often travels alongside the other things service members and their families carry, including PTSD and anxiety. If medication has not brought the relief you were hoping for, TMS is worth understanding, and for TriCare beneficiaries it is a covered option. What Is TMS Therapy? TMS (transcranial magnetic stimulation) is a non-invasive, FDA-cleared treatment for depression. It uses targeted magnetic pulses to stimulate the areas of the brain involved in mood regulation. There is no anesthesia and no sedation. Most people drive themselves to and from sessions and go straight back to their day. It is usually considered when antidepressant medications have not provided enough relief, which is also the point at which TriCare coverage becomes relevant. Does TriCare Cover TMS? Yes, for major depressive disorder . TriCare covers TMS as an outpatient treatment for adults with major depressive disorder. TriCare is accepted at Inspire TMS Denver. Coverage still depends on your specific plan and on the documentation your provider submits, so it is not something to guess at. Rather than have you work it out alone, the clinic verifies your benefits before treatment begins and gives you an estimate of any out-of-pocket cost, so there are no surprises once you start. PTSD, Depression, and What TriCare Actually Covers This is the part worth being straight about, because it affects whether your treatment gets approved. TMS is FDA-cleared and TriCare-covered for major depressive disorder. It is not covered as a standalone treatment for PTSD. A lot of people in the military community come in thinking of PTSD as the main issue, and depression is very often part of that same picture. Where major depressive disorder is present and documented, that is the diagnosis that opens the door to TMS coverage. You do not need to untangle this yourself. During your evaluation, the clinical team determines the correct primary diagnosis and handles the paperwork that goes to TriCare. What helps most is being open about your full history, including your mood, your medication trials, and what has and has not worked. Who Does TriCare Cover? TriCare serves active duty service members, activated National Guard and Reserve members, military retirees, and their families. If you are a veteran who separated without retiring, your coverage may run through the VA rather than TriCare, which is a different pathway. If you are not sure which applies to you, the screening call is the fastest way to find out where you stand.
Dental clinician examining a seated patient in a bright clinic with panoramic windows.
By Sam Clinch August 12, 2026
Quick Answer: As of August 2025, TMS is FDA-cleared for adolescents aged 15 to 21 with major depressive disorder, as an add-on (adjunct) to antidepressant medication for teens who haven't responded adequately to medication alone. It's non-invasive, drug-free, and done without sedation. It is not a replacement for medication or therapy, and at our clinic, a teen must have an existing psychiatrist and therapist to begin. This post explains what the clearance actually covers, what treatment involves, and how to tell if it's worth exploring for your child. If your teenager has been struggling with depression and medication hasn't been enough, you've probably reached the point of asking what else exists. TMS is now a real, FDA-cleared option for adolescents, but there's a lot of loose language online about what it is and who it's for. Here's the accurate version, written for parents who want the facts without the hype. Is TMS FDA-Cleared for Teenagers? Yes, with specific limits worth understanding. In August 2025, the FDA cleared the MagVenture TMS system , the equipment we use, as an adjunct treatment for major depressive disorder in adolescent patients aged 15 to 21. (Other manufacturers received similar adolescent clearances around the same period.) Two details matter here, because a lot of websites blur them: It's FDA-cleared, not "FDA-approved." Those are different regulatory pathways, and cleared is the correct term for TMS devices. The clearance covers ages 15 to 21, not an open-ended "15 and up." There's a defined upper bound. We're precise about this because when the topic is treating a minor, the details are the whole point. What "Adjunct" Actually Means This is the part most worth understanding. The FDA cleared TMS for adolescents as an adjunct, which means an add-on used alongside antidepressant medication, for teens who have not responded adequately to that medication on its own. It is not cleared as a replacement for medication, and the evidence in adolescents is strongest when TMS is added to an existing antidepressant rather than used by itself. So the honest framing is this: TMS is a way to boost the effect of treatment your teen is already on when that treatment hasn't been enough, not a way to take them off their medication. Any clinic suggesting TMS can simply replace a teenager's antidepressant is getting ahead of what the science and the clearance actually support. How TMS Works and What Treatment Involves TMS uses targeted magnetic pulses to stimulate a region of the brain involved in mood regulation, the left dorsolateral prefrontal cortex. It's non-invasive: nothing enters the body, there's no sedation or anesthetic, and your teen is fully awake throughout. Practically, for your child that means: Short daily sessions. Treatment sessions run about 18.5 minutes, with patients typically in and out of the office within half an hour. A weekday schedule. A standard course runs daily on weekdays over about six weeks, followed by a short taper of two to three weeks. No downtime. Because there's no sedation, teens can return to school and normal activities immediately after each session. Generally mild side effects. When they occur, side effects are usually localized: some scalp discomfort at the treatment site during the pulses, which typically stops as soon as the session ends, and occasional headaches that usually respond to over-the-counter pain relief. Often there are no side effects at all. TMS does not involve the sedation or systemic medication effects that come with some other treatments, and it is not associated with effects on memory or concentration. Why Consider TMS for a Teen? Adolescence is a period when depression often appears for the first time, and standard treatments don't always work. Some teens don't respond to the medications they try; others struggle with side effects or find it hard to stay on medication consistently. When that's the situation, a non-drug option that adds to their existing care can be genuinely valuable. That's the role TMS plays here: another tool for teens whose depression hasn't lifted enough with medication and therapy alone, not a first move and not a standalone fix.
Five medical staff in blue scrubs standing in a clinic hallway, smiling at the camera.
By Sam Clinch August 11, 2026
Quick Answer: A TMS assessment is a psychiatric evaluation, not a treatment session. You'll sit down with Dr. Clinch to go through your history, your current symptoms, and what you've already tried, and he'll screen for the safety factors that determine whether TMS is appropriate for you . You'll also complete baseline symptom scoring and go through the practical side: insurance, cost, and scheduling. Nothing is done to you that day, and there's no obligation to proceed. This post walks through exactly what to expect. Booking a first appointment for something you've never done is uncomfortable when you don't know what it involves. A TMS assessment is straightforward and low-pressure, but "assessment" can sound clinical and vague. Here's a plain account of what actually happens, start to finish. Who You'll See Your assessment is with Dr. Samuel Clinch, a board-certified psychiatrist and the clinic's founder. This matters more than it might sound. At a lot of clinics, the first person you meet is a coordinator or a technician, and the doctor comes later, if at all. Here, the clinical evaluation is done by the psychiatrist who will oversee your care, because deciding whether TMS is right for you is a medical judgment, not an intake form. That also means you can ask real questions and get real answers in the room, rather than being handed a brochure and a follow-up number. The Conversation: Your History and Symptoms The core of the assessment is a proper conversation about what's brought you here. Expect to cover: What you're experiencing now. Your symptoms, how long they've been going on, and how they affect your day-to-day life. What you've already tried. Medications, therapy, other treatments, and how you responded to each. TMS is often considered when medication hasn't given full relief, so this history genuinely shapes the recommendation. Your medical and psychiatric background. Diagnoses, relevant health conditions, and current medications. What you're hoping for. Realistic goals matter, and they help set expectations for what treatment can and can't do. You'll also complete baseline symptom scoring, usually the PHQ-9 for depression or the GAD-7 for anxiety. These give a fixed starting point, so that if you go ahead with treatment, improvement is measured against where you began rather than estimated from memory. The Safety Screening TMS is well tolerated , but it isn't suitable for everyone, and part of the assessment is a careful safety screen. This is where seemingly small questions carry weight. Dr. Clinch will check for things like a history of seizures, significant head injury, and any magnetically sensitive implants or metal above the neck, since the treatment uses magnetic pulses. He'll also screen for conditions such as bipolar disorder, because that affects how treatment is approached. If some of the intake questions feel unrelated to your mood, this is why. They're there to make sure treatment is safe and appropriate for you specifically, and they're not a formality.
Clinician adjusting EEG headset on patient in a blue chair near a window
By Sam Clinch August 11, 2026
Quick Answer: Improvement from TMS is usually gradual, not a switch that flips. Most people start noticing change in the middle of a course, often between sessions 20 and 30, not after the first session. It's measured on real symptom scales, and it comes in two levels: a response (symptoms at least halved) and remission (no longer scoring as depressed). This post sets honest expectations about what changes, when, and how it's actually measured, using our own tracked results rather than generic claims. Most content about TMS results falls into one of two traps: vague promises ("feel like yourself again") or cherry-picked miracle stories. Neither tells you what to actually expect. Here's a straight account of what improvement looks like before, during, and after a course of TMS. Measured, not hyped. What "Improvement" Actually Means Improvement in TMS isn't something we take your word for. It's tracked against a baseline using standard clinical scales. For depression, that's the PHQ-9; for anxiety, the GAD-7. You complete these at the start and at intervals through treatment, so change is measured rather than guessed at. There are two levels of improvement worth knowing, because they're different things: Response means your symptoms have at least halved from where they started. For most people who reach it, that's a meaningful, life-changing shift. Remission means you're no longer scoring in the depressed range at all. Not everyone reaches remission, and some people respond without fully remitting. Being clear about that distinction upfront is part of setting honest expectations. Before Treatment: Your Baseline The "before" picture is your baseline score, plus an honest conversation about what you're actually living with day to day: sleep, energy, motivation, the things depression or anxiety has been flattening. This matters more than it sounds. Depression distorts your memory of your own state. When you're in it, it's hard to recall feeling otherwise, and later it can be hard to appreciate how far you've come. A baseline score gives you and Dr. Clinch a fixed reference point, so improvement becomes something you can see on paper, not just try to sense.
Dental professional examining a patient reclining in a chair with medical equipment nearby
By Sam Clinch July 22, 2026
Quick Answer: A first course of TMS that didn't deliver the relief you hoped for isn't the end of the road. The right next step depends on which situation you're in — TMS that worked and then faded, or TMS that never quite landed. Options range from a repeat course or maintenance sessions to changing the protocol itself, and for people who responded the first time, a repeat course works again in the large majority of cases. This post covers both paths honestly. Finishing a full course of TMS and not feeling the shift you were hoping for is discouraging, and it can feel like you've used up your last option. You haven't. "It didn't work" actually covers a few different outcomes, and each one points to a different, concrete next step. Knowing which one you're in is the first move. First, which kind of "didn't work" is this? Before talking about what to change, it helps to name what happened. Clinicians usually sort first-course outcomes into three groups: You responded, then slipped. Symptoms improved during or after treatment, then crept back weeks or months later. You partially responded. You felt some improvement, but not enough to call it a real change. You didn't respond. You completed the sessions and noticed little or no difference. Two terms come up a lot here. Response means a meaningful drop in symptoms - you feel noticeably better. Remission means your symptoms have largely resolved. A first course can produce a response without full remission, and that distinction shapes what comes next. If TMS worked and then faded: repeat courses and maintenance This is the most common version of "it didn't last," and it's also the most encouraging. Depression is a relapsing condition, and a fading response is not the same as TMS failing. For people who responded the first time and later relapsed, a repeat course tends to work again. Across published data, roughly 80–90% of patients who return for retreatment respond a second time , and one large multi-site study found about 84% of patients who needed another course or maintenance sessions improved again. Responding earlier and more strongly in your first course is associated with longer-lasting, more repeatable results. What is maintenance TMS? Instead of a full repeat course, some patients move to maintenance TMS — a lighter, individualized schedule of sessions (anywhere from weekly to monthly) designed to hold a good result in place. Maintenance is decided case by case, is billed per session (currently $75), and isn't covered by insurance. You can read more on our maintenance and retreatment blog and our pricing guide . If the first course didn't land: adjusting the protocol A second attempt shouldn't be a carbon copy of the first. If you saw little benefit, the useful question is what to change, and there's usually more to adjust than people realize. Re-mapping and coil positioning. Where the coil sits matters. A careful re-check of your treatment target and motor threshold can meaningfully change the dose your brain actually receives. Protocol and dose. Session count, pulse dose, and intensity can be revised. Some patients switch to or add iTBS (intermittent theta burst stimulation), a shorter session format, or an accelerated schedule that condenses treatment into a much smaller window. A longer or re-targeted course. Extending treatment or adjusting the target region is sometimes appropriate. None of this guarantees a different outcome, but it means a second round can be genuinely different from the first rather than a repeat of something that didn't help.
Show More